The fact of life is that death is imminent and it effects every one. It's easy to get depressed. What is there to really live for? Is it just plugging along here on earth and then dying? What are we doing?
But this gives hope:
50 Now this I say, brethren, that flesh and blood cannot inherit the kingdom of God; nor does corruption inherit incorruption. 51 Behold, I tell you a mystery: We shall not all sleep, but we shall all be changed— 52 in a moment, in the twinkling of an eye, at the last trumpet. For the trumpet will sound, and the dead will be raised incorruptible, and we shall be changed. 53 For this corruptible must put on incorruption, and this mortal must put on immortality. 54 So when this corruptible has put on incorruption, and this mortal has put on immortality, then shall be brought to pass the saying that is written: “Death is swallowed up in victory.”[g] 55 “ O Death, where is your sting?[h] O Hades, where is your victory?”[i] 56 The sting of death is sin, and the strength of sin is the law. 57 But thanks be to God, who gives us the victory through our Lord Jesus Christ. (1 Corinthians 15:50-57)
There is something else, something new that is coming. God will make all things new...in a twinkling of an eye (which, as I think C.S. Lewis mentioned, is such a cheerful and wistful action). There is a point and something better is coming.
So, in light of this:
Therefore, my beloved brethren, be steadfast, immovable, always abounding in the work of the Lord, knowing that your labor is not in vain in the Lord. (1 Corinthians 15:58)
We keep going and in the middle of entropy and death, we look forward to something new.